The plain fact is that the physical structure of the human being is a joke in itself: a flat, crude, unanswerable disproof of any nonsense about "intelligent design." The reproductive and eliminating functions (the closeness of which is the origin of all obscenity) were obviously wired together in hell by some subcommittee that was giggling cruelly as it went about its work.
Humor, if we are to be serious about it, arises from the ineluctable fact that we are all born into a losing struggle. Those who risk agony and death to bring children into this fiasco simply can't afford to be too frivolous.